Immunity· Ryota Asahina, Fuuka Minami, Satoshi Nakamizo, Toshiya Miyake, Satoru Yonekura, Toshiaki Kogame, Shuto Kanameishi, Kosuke Katsuo, Hiroyuki Irie, Saeko Nakajima, Takashi Nomura, Akihiko Kitoh, Gyohei Egawa, Kenji Kabashima·· 5 天前AI 评分42
皮肤驻留CXCR6+记忆CD4+ T细胞与树突状细胞形成真皮血管周围细胞簇，驱动过敏性皮炎复发
Skin-resident CXCR6+ memory CD4+ T cells and dendritic cells form dermal perivascular hubs that drive relapse in allergic dermatitis
AI 导读
Asahina等鉴定出一种驱动过敏性皮炎复发的致病性CXCR6+ CD4+组织驻留记忆T细胞亚群。该亚群通过依赖CXCL16的机制与CD301b+ cDC2聚集并得以维持，提示这一T细胞与树突状细胞生态位可能成为治疗靶点。
来源：Immunity · cell.com