Cell Genomics· Seunghyun Wang, Mingyun Bae, Jinhao Wang, Boxun Zhao, Khue Nguyen, Shayna Mallett, Jessica A. Switzenberg, Steven J. Losh, Corinne E. Sexton, Benpeng Miao, Shihua Dong, Xi Zeng, Ziying Wang, Torrin L. McDonald, Camille Mumm, Rohini K. Gadde, Arnaz Maryam Tariq, Zhuofu Chen, William C. Feng, Aidan Burn, Junseok Park, Chong Chu, Hui Shen, Ting Wang, Alexander E. Urban, Xiaowei Zhu, Heng Li, Kathleen H. Burns, Hye-Jung E. Chun, Peter J. Park, SMaHT MEI Working Group, Alan P. Boyle, Ryan E. Mills, Weichen Zhou, Eunjung Alice Lee·· 19 小时前AI 评分40
用于绘制人体组织体细胞逆转座图谱的多平台框架
Multi-platform framework for mapping somatic retrotransposition in human tissues
AI 导读
Wang等建立了经过系统基准评估的多平台框架，整合长读长测序与基因组组装，以准确检测体细胞移动元件插入并追溯其来源。该框架在正常人体组织中揭示了罕见的体细胞L1插入，为研究移动元件如何在生命过程中重塑基因组提供支持。
来源：Cell Genomics · cell.com