Cell Reports Medicine· Vinicius A. Schoeps, Pavan Bhargava, Gina Chang, Danielle J. Caruso, Dohee Kim, Akash Virupakshaiah, Janet Chong, Gregory Aaen, Jennifer S. Graves, Leslie A. Benson, Mark P. Gorman, Mary Rensel, Aaron W. Abrams, Soe S. Mar, Timothy Lotze, Tanuja Chitnis, Amy T. Waldman, Lauren B. Krupp, Moses Rodriguez, Jan-Mendelt Tillema, John W. Rose, Teri Schreiner, T. Charles Casper, Helen Tremlett, John W. Newman, Kamil Borkowski, Emmanuelle Waubant, the US Network of Pediatric MS Centers·· 19 小时前AI 评分39
短链脂肪酸丙酸与儿童起病多发性硬化的疾病活动度相关
Propionate, a short-chain fatty acid, is associated with disease activity in pediatric-onset multiple sclerosis
AI 导读
Schoeps等发现，在多发性硬化起病不久的年轻患者中，血浆及粪便丙酸水平较高均与较低的临床及影像学疾病活动度相关。这些发现提示，肠道微生物来源的短链脂肪酸可能调节早期炎症活动，支持开展靶向补充的临床试验。
来源：Cell Reports Medicine · cell.com