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The Lancet · Online First· Jasper Boeddinghaus, Michael Kunz, Pedro Lopez-Ayala, Aleem Khand, Kenji Inoue, James Hatherley, Joseph Miller, Kristina Lambrakis, Joshua Emakhu, Bernard Cook, Paul Collinson, Cynthia Papendick, Sazzli Kasim, Farina Mohd Salleh, Andrea Wiencierz, Paolo Bima, Luca Crisanti, Luca Koechlin, Michael Christ, Òscar Miró, Fulvio Morello, Peiman Nazerian, Mohammed Abubakr, Dominik Roth, Felix Mahfoud, Richard Riley, James McCord, Derek P Chew, Christian Mueller, Global 0/1 h Consortium·· 4 小时前精选AI 评分62

疑似心肌梗死患者0/1 h与0/3 h路径比较:随机试验个体参与者数据荟萃分析

[Articles] Performance of 0/1 h versus 0/3 h pathways in patients with suspected myocardial infarction: a systematic review and individual participant data meta-analysis of randomised controlled trials

AI 导读

一项随机对照试验的系统综述和个体参与者数据荟萃分析显示,疑似心肌梗死患者采用0/1 h或0/3 h路径时,短期不良事件率均较低,但合并安全性估计仍不精确。平均而言,提前复测心肌肌钙蛋白未缩短急诊停留时间,也未明确提高直接出院比例。研究间存在显著异质性,医院从0/3 h转向0/1 h路径时,应同时考虑更广泛的诊断及组织运行因素。

推荐理由

两种路径的短期不良事件率均较低,但合并安全性估计不精确且研究间异质性明显,限制了结果向不同医疗系统的外推。

来源:The Lancet · Online First · thelancet.com