Cancer Cell· Serena Porcari, Laura A. Bolte, Johannes R. Björk, Arielle Elkrief, Lisa Derosa, Margherita Ferrari, Angelo Maria Pezzullo, Andrea Severino, William Fusco, Meriem Messaoudene, Carolina Alves Costa Silva, Marine Fidelle, Bertrand Routy, Laura Mählmann, Andrew M. Thomas, Chiara Ciccarese, Camilla Nero, Anna Fagotti, Giampaolo Tortora, Antonio Gasbarrini, Roberto Iacovelli, Emilio Bria, Andy Futreal, Jennifer McQuade, Guido Kroemer, Geke A.P. Hospers, Jacco J. de Haan, Jennifer Wargo, Nicola Segata, Rinse K. Weersma, Gianluca Ianiro, Laurence Zitvogel, Seerave Global Oncobiome Network·· 19 小时前AI 评分50
抗生素暴露与肿瘤免疫治疗结局的更新荟萃分析及临床应用
Antibiotics and outcomes of cancer immunotherapy: An updated meta-analysis and clinical applications
AI 导读
一项纳入116个队列、近98,000名接受免疫检查点抑制剂（ICI）治疗患者的更新荟萃分析显示，抗生素暴露与较差的总生存期和无进展生存期显著相关。研究还概述了这一治疗场景下的抗生素合理使用及微生物组策略，以预防和修复菌群失调。
来源：Cancer Cell · cell.com