Cell Systems· Chuyu Xiao, Yaqiong Guo, Chunlin Li, Yuan Liu, Ting Wang, Haitao Liu, Yalong Wang, Xiyue Chen, Mengxian Zhang, Ronghui Tan, Zhi Fang, Huidong Liu, Zhicheng Yao, Xiong Lei, Jianhua Qin, Ye-Guang Chen·· 2026-09-10AI 评分36
通过多类器官系统模拟生理性吸收与代谢，评估抗肿瘤药物
Evaluation of anti-tumor drugs by simulating physiological absorption and metabolism with a multi-organoid system
AI 导读
Xiao等建立了整合肠道吸收、肝脏代谢和肿瘤反应的多类器官系统，用于评估抗肿瘤药物。该系统可捕捉单纯肿瘤培养所忽略的药物活化与失活过程，为预测药物疗效和毒性提供更符合生理情况的方法。
来源：Cell Systems · cell.com