Cell Reports Medicine· Shaoqing Liu, Hongbing Liu, Mengying Zhang, Kaiyuan Guo, Shilin Tong, Nuo Jiang, Jinxue Zhou, Linlin Yan, Mien-Chie Hung, Chenhao Zhou, Yanzhao Zhou, Min Xu·· 1 天前AI 评分35
靶向 MMGT1 增强三阴性乳腺癌免疫治疗疗效
Targeting MMGT1 enhances immunotherapy efficacy in triple-negative breast cancer
AI 导读
Liu等发现，膜镁转运蛋白1（MMGT1）高表达通过衰老相关分泌表型诱导CD8+ T细胞耗竭，促进免疫逃逸。靶向MMGT1有望成为提高三阴性乳腺癌抗PD-1免疫治疗疗效的策略。
来源：Cell Reports Medicine · cell.com