Science Translational Medicine· Baomei Wang, Isabel Ishizuka, Emel Esen, Ji Li, Cecilia Chiu, Yonglian Sun, Zhonghua Lin, Dhaya Seshasayee, Aija Kusi, Yu Zhong, Wendy Halpern, Adeyemi O. Adedeji, Lanlan Yu, Peter Tran, Zhaojun Yin, Shang-Fan Yu, Geoff Del Rosario, Yoko Oei, Yagai Yang, Jill Schartner, Mary Ann Go, Giulia Protti, Soren Muller, Cong Wu, Ran Li, Genee Lee, James T. Koerber, Sascha Rutz, Teemu T. Junttila·· 16 小时前AI 评分27
CCR8xCD3 T细胞衔接双特异性抗体（TCB）通过T细胞介导的肿瘤内调节性T细胞清除促进临床前小鼠模型的抗肿瘤免疫
T cell–mediated depletion of intratumoral regulatory T cells using a CCR8xCD3 T cell–engaging bispecific antibody (TCB) promotes antitumor immunity in preclinical mouse models
AI 导读
CCR8xCD3 T细胞衔接双特异性抗体（TCB）在临床前小鼠模型中，通过T细胞介导的肿瘤内调节性T细胞清除促进抗肿瘤免疫。该研究发表于Science Translational Medicine，所提供内容未披露具体实验设计、样本量或效应量。
来源：Science Translational Medicine · science.org