Cancer Cell· Anand G. Patel, Orr Ashenberg, Natalie B. Collins, Justina McEvoy, Melody Allensworth-James, Felipe Segato Dezem, Samantha Turk, Natalie Geiger, Arjumand Wani, Luke Zhang, Åsa Segerstolpe, Sizun Jiang, Cody Ramirez, Michal Slyper, Xin Huang, Chiara Caraccio, Hongjian Jin, Heather Sheppard, Meifen Lu, Ke Xu, Ti-Cheng Chang, Brent A. Orr, Selene Koo, Abbas Shirinifard, Chia-Wei Hsu, Richard H. Chapple, Amber Shen, Michael R. Clay, Ruth G. Tatevossian, Colleen Reilly, Jaimin Patel, Marybeth Lupo, Cynthia Cline, Danielle Dionne, Caroline B.M. Porter, Julia Waldman, Yunhao Bai, Bokai Zhu, Irving Barrera, Evan Murray, Sébastien Vigneau, Sara Napolitano, Isaac Wakiro, Jingyi Wu, Grace Grimaldi, Laura Dellostritto, Karla Helvie, Asaf Rotem, Ana Lako, Nicole Cullen, Kathleen L. Pfaff, Åsa Karlström, Judit Jané-Valbuena, Ellen Todres, Aaron Thorner, Paul Geeleher, Scott J. Rodig, Xin Zhou, Bruce E. Johnson, Gang Wu, Fei Chen, Jiyang Yu, Yury Goltsev, Jasmine Plummer, Garry P. Nolan, Orit Rozenblatt-Rosen, Haitao Pan, Aviv Regev, Elizabeth Stewart, Michael A. Dyer·· 9 天前AI 评分42
空间组学解析神经母细胞瘤的肾上腺素能与间充质细胞状态
Spatial omics resolves adrenergic and mesenchymal cell states in neuroblastoma
AI 导读
Patel等在54例神经母细胞瘤肿瘤中识别出间充质（MES）肿瘤细胞，并发现较高MES评分可预测较差的患者结局。研究结合六种空间组学平台与单细胞/单核RNA测序，利用患者来源异种移植模型的特征识别MES肿瘤细胞。
来源：Cancer Cell · cell.com